CENTRO DE INVESTIGACION DEL CANCER

  • Laboratorio 15

Dr. Atanasio Pandiella Alonso

ROLE OF SOLUBLE FACTORS AND MEMBRANE RECEPTORS IN PROCESSES OF PROLIFERATION, DIFFERENTIATION AND ONCOGENIC TRANSFORMATION


Biography

Dr. Pandiella obtained his Ph.D degree in Medicine and Surgery from the University of Santiago de Compostela in 1987. His scientific training outside Spain includes four years (1985-1989) as a pre- and post-doctoral student at the Ospedale San Raffaele in Milan and three years at the Memorial Sloan Kettering Cancer Center (1989-1992 New York, U.S.A)
Later, for one year, Dr. Pandiella worked at the Department of Physiology of the University of Las Palmas in the Canary Islands. From 1994 up to 2001, he has been on the team of the Institute of Biochemical Microbiology of the University of Salamanca. His research line focuses on the functional characterisation of molecules involved in the genesis and promotion of different solid tumours in humans, in particular breast cancers.

Dr. Atanasio  Pandiella Alonso
Contact


Dr. Atanasio Pandiella
Investigador científico del CSIC
Laboratorio Nº 15

923 294 815
923 294 743
atanasio(arroba)usal(.)es

Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
Campus Universitario Miguel de Unamuno s/n
37007 Salamanca
SPAIN

Areas of Research


Our laboratory is involved in the study of proteins that participate in processes of intercellular communication. In particular, we are interested in growth factors and their receptors. Some of these proteins are directly related to the maintenance of tissue homeostasis and their deregulation has been related to pathological processes of considerable social import, such as oncogenesis and neurodegenerative diseases, such as Alzheimer\'s syndrome. Currently we are pursuing several lines of research:\r\n\r\n1- Cellular mechanisms involved in the proliferative response induced upon activation of growth factor receptors.\r\n\r\n2- Evaluation of the role of receptors from the HER family and their ligands in processes of proliferation and tumour genesis.

Projects
  • Ministerio de Economía y Competitividad (2013-2016)

    Señalización por receptores ERBB/HER

  • Ministerio de Economía y Competitividad/Instituto de Salud Carlos III. (2013-2016)

    Red Temática de Investigación Cooperativa en Cáncer (RD12/0036/0003),

  • MINISTERIO DE CIENCIA E INNOVACION (2010-2013)

    LA RED DE SEÑALIZACION NEUREGULINAS-RECEPTORES ERBB

  • Junta de Castilla y Leon (2009-2010)

    P-REX, Una nueva proteina implicada en la señalización intracelular por receptores ErbB

  • Phamamar (2009-2009)

    CARACTERIZACION DE LA ACTIVIDAD ANTITUMORAL DE COMPUESTOS DE ORIGEN MARINO

  • Instituto Biomar, S.A. (2008-2009)

    Descubrimiento de compuestos bioactivos evaluando diferentes librerias de muestras microbianas en una nueva plataforma de ensayos biológicos.

  • CSIC (2006-2000)

    BIOLÓGÍA DE LAS NEUREGULINAS Y SEÑALIZACIÓN POR SUS RECEPTORES

  • Ministerio de Ciencia y Tecnologia (2003-2006)

    Biología de las neurogulinas y señalización por sus receptores

  • PORTUGAL (2003-2004)

    Dotación asociada a becario

  • INSTITUTO DE SALUD CARLOS III (2003-2007)

    MIELOMA MULTIPLE Y OTRAS GANMAPATÍAS DE LA GENESIS A LA TERAPEÚTICA.

  • ASOCIACION ESPAÑOLA CONTRA EL CANCER (2002-2002)

    Nuevas estrategias terapeuticas en el tratamiento del mieloma múltiple: evaluación molecular de su mecanismo de acción

  • INSTITUTO DE SALUD CARLOS III (2001-2003)

    Participación de la via ERK5 en la transducción de señales por receptores ERBB

Junta de Castilla y León Ministerio de economía y competitividad Fondo europeo de desarrollo regional
NCBI-PubMed Articles
Publications

(*) Means equal contribution as senior authors.



2021
2020
2019

MEK5 promotes lung adenocarcinoma.

Sánchez-Fdez A, Ortiz-Ruiz MJ, Re-Louhau MF, Ramos I, Blanco-Múñez Ó, Ludeña D, Abad M, Sánchez-Martín M, Pandiella A, Esparís-Ogando A, 
Eur Respir J; 2019; 53(2); 1801327; 30442718


2018
2017
2016

Circulating DNA and Survival in Solid Tumors.

Ocaña A, Díez-González L, García-Olmo DC, Templeton AJ, Vera-Badillo F, José Escribano M, Serrano-Heras G, Corrales-Sanchez V, Seruga B, Andrés-Pretel F, Pandiella A, Amir E, 
Cancer Epidemiol Biomarke; 2016; 25(2); 399-406; 26604269


2015
2014
2013
2012
2011
2010
2009
2008

Neuregulins and cancer.

Montero JC, Rodríguez-Barrueco R, Ocaña A, Díaz-Rodríguez E, Esparís-Ogando A, Pandiella A, 
Clin. Cancer Res.; 2008; 14(11); 3237-41; 18519747


2007
2006
2005

Multifunctional role of Erk5 in multiple myeloma.

Carvajal-Vergara X, Tabera S, Montero JC, Esparís-Ogando A, López-Pérez R, Mateo G, Gutiérrez N, Parmo-Cabañas M, Teixidó J, San Miguel JF, Pandiella A, 
Blood; 2005; 105(11); 4492-9; 15692064


2004
2003
2002
2000
1999
1996
1993
1992
1991
1990
1989
1988
1987
1986

[Pharmacologic treatment of obesity].

Villanueva L, Carruba MO, Peñalva A, Pandiella A, Díaz Y, Casanueva FF, Cabezas Cerrato J, Fernández-Cruz A, 
Rev Clin Esp; 1986; 179(6); 317-22; 3797737


Patents
  • Multiple myeloma treatments
    Marín Pablo Manuel Avilés / Ocio Enrique / Miguel Jesús San / Pandiella Atanasio
    US2011076343 (A1) WO2009138509 (A1) AU2009248039 (A1) CA2724206 (A1) CN102065865 (A) EP2303274 (A1) JP2011520846 (A) KR20110028454 (A) MX2010012358 (A) NZ589270 (A); 2008-05-16

  • Improved antitumoral treatments Faircloth Glynn
    Thomas / Avilés Marín Pablo Manuel; Lepage Doreen / San Miguel Izquierdo Jesús / Pandiella Atanasio
    US2009246168 (A1) WO2007101235 (A3) EP2029155 (A4) KR20080105123 (A) CN101389347 (A) AU2007220050 (A1) CA2643238 (A1) JP2009528379 (A) MX2008010999 (A) NO20084047 (A) RU2008138560 (A); 2006-02-28

Group
  • Dr. Atanasio  Pandiella Alonso Dr. Atanasio Pandiella Alonso

    Dr. Atanasio Pandiella Alonso

    ROLE OF SOLUBLE FACTORS AND MEMBRANE RECEPTORS IN PROCESSES OF PROLIFERATION, DIFFERENTIATION AND ONCOGENIC TRANSFORMATION

    Telf.:

    Fax:

    Email: atanasio@usal.es


    Contact

    Dr. Atanasio Pandiella
    Investigador científico del CSIC
    Laboratorio Nº 15

    923 294 815
    923 294 743
    atanasio(arroba)usal(.)es

    Centro de Investigación del Cáncer (Universidad de Salamanca-CSIC)
    Campus Universitario Miguel de Unamuno s/n
    37007 Salamanca
    SPAIN


    Biography

    Dr. Pandiella obtained his Ph.D degree in Medicine and Surgery from the University of Santiago de Compostela in 1987. His scientific training outside Spain includes four years (1985-1989) as a pre- and post-doctoral student at the Ospedale San Raffaele in Milan and three years at the Memorial Sloan Kettering Cancer Center (1989-1992 New York, U.S.A)
    Later, for one year, Dr. Pandiella worked at the Department of Physiology of the University of Las Palmas in the Canary Islands. From 1994 up to 2001, he has been on the team of the Institute of Biochemical Microbiology of the University of Salamanca. His research line focuses on the functional characterisation of molecules involved in the genesis and promotion of different solid tumours in humans, in particular breast cancers.

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